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The curse of an evil witch turns a plain young hat-maker, Sophie, into an old woman. Sophie runs away to confront the witch and become young again when she rescues a trapped animated scarecrow.

Rintaro Okabe is a self-proclaimed "mad scientist" who believes that an international scientific organization named SERN is conspiring to reshape the world according to its own interests. He and his friend Itaru Hashida inadvertently create a gadget able to send messages to the past.

After accidentally killing a government official’s son in a fight, Mugen and Jin are seized, and are sentenced for execution. Fuu successfully saves the two warriors, and hires them to accompany her during her search for a samurai “who smells of sunflowers” which may lead to her father.

Gurren Lagann takes place in a fictional future where Earth is ruled by the Spiral King, Lordgenome, who forces mankind to live in isolated subterranean villages. These villages have no contact with the surface world or other villages, and are under constant threat of earthquakes.