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Fullmetal Alchemist: Brotherhood, commonly referred to as FMAB is the second adaptation of the hit manga series Fullmetal Alchemist by Hiromu Arakawa. In 2003, shortly after the manga began its run, the first adaptation titled Fullmetal Alchemist was made.

The world is beginning to get back on it's feet and rebuild after the destruction that lied in Sephiroth's wake. Not all is going well, however, as a new disease known as Geostigma threatens the world.